Peter J Scammells Selected Research

Adenosine A1 Receptor

1/2022	Examining the Role of the Linker in Bitopic N6-Substituted Adenosine Derivatives Acting as Biased Adenosine A1 Receptor Agonists.
1/2021	Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells.
1/2019	Probe dependence of allosteric enhancers on the binding affinity of adenosine A1 -receptor agonists at rat and human A1 -receptors measured using NanoBRET.
1/2018	A Structure-Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists.
9/2010	A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate.

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Peter J Scammells Research Topics

Disease

10	Malaria 10/2021 - 06/2013
9	Schizophrenia (Dementia Praecox) 01/2022 - 07/2013
8	Neoplasms (Cancer) 01/2021 - 02/2014
6	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 06/2013
5	Bradycardia 01/2022 - 03/2014
3	Reperfusion Injury 01/2022 - 09/2010
3	Cognitive Dysfunction 01/2022 - 06/2014
3	Parkinson Disease (Parkinson's Disease) 01/2016 - 06/2013
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022 - 01/2018
2	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2018
2	Pathologic Processes 01/2020 - 01/2019
2	Infections 01/2016 - 11/2014
2	Ischemia 04/2012 - 09/2010
1	Melanoma (Melanoma, Malignant) 01/2021
1	Heart Failure 01/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Neuralgia (Stump Neuralgia) 01/2021
1	Tachycardia (Tachyarrhythmias) 01/2021
1	Hyperprolactinemia 11/2019
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Pain (Aches) 01/2018
1	Necrosis 10/2016
1	Myocardial Infarction 10/2016
1	Hypertrophy 10/2016
1	Chromosome Aberrations (Chromosome Abnormalities) 08/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2015
1	Parasitic Diseases (Parasitic Disease) 11/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2013
1	Colonic Neoplasms (Colon Cancer) 02/2009

Drug/Important Bio-Agent (IBA)

7	Adenosine (Adenocard)FDA LinkGeneric 01/2022 - 09/2010
5	Adenosine A1 ReceptorIBA 01/2022 - 09/2010
5	Pharmaceutical PreparationsIBA 01/2021 - 11/2013
5	Noscapine (Narcotine)IBA 01/2021 - 08/2015
4	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2022 - 06/2014
4	AminopeptidasesIBA 01/2019 - 06/2013
4	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2019 - 11/2013
4	LigandsIBA 01/2015 - 06/2013
3	VCP746IBA 01/2022 - 10/2016
3	Antimalarials (Antimalarial Agents)IBA 01/2019 - 11/2014
2	Cytotoxins (Cytolysins)IBA 01/2021 - 01/2018
2	TubulinIBA 01/2021 - 01/2019
2	Antipsychotic Agents (Antipsychotics)IBA 11/2019 - 11/2016
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2018 - 06/2013
2	Cholinergic Agents (Cholinergics)IBA 01/2018 - 07/2013
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 11/2014
2	AntigensIBA 01/2016 - 11/2014
1	Phenol (Carbolic Acid)FDA Link 10/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021
1	compound 20IBA 01/2021
1	capadenosonIBA 01/2020
1	Clozapine (Clozaril)FDA LinkGeneric 11/2019
1	Haloperidol (Haldol)FDA LinkGeneric 11/2019
1	Antitussive Agents (Antitussives)FDA Link 01/2019
1	ZincIBA 01/2019
1	CD13 Antigens (Alanine Aminopeptidase)IBA 01/2019
1	Morphine (MS Contin)FDA LinkGeneric 01/2018
1	Opioid Analgesics (Opioids)IBA 01/2018
1	Cholinergic ReceptorsIBA 01/2018
1	Analgesics (Analgesic Drugs)IBA 01/2018
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 10/2016
1	Messenger RNA (mRNA)IBA 10/2016
1	Biomarkers (Surrogate Marker)IBA 10/2016
1	Leucine (L-Leucine)FDA Link 10/2016
1	Atrial Natriuretic Factor (ANF)IBA 10/2016
1	InterleukinsIBA 10/2016
1	Mitogen-Activated Protein KinasesIBA 02/2015
1	VaccinesIBA 11/2014
1	AntibodiesIBA 11/2014
1	Peptides (Polypeptides)IBA 11/2014
1	artemisinin (artemisinine)IBA 11/2014
1	Urea (Carbamide)FDA LinkGeneric 02/2014
1	LactonesIBA 02/2014
1	Cyclic EthersIBA 02/2014
1	Biological ProductsIBA 02/2014
1	cariprazineIBA 11/2013
1	Muscarinic M1 ReceptorIBA 06/2013
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 06/2013
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2012
1	N(6)-cyclopentyladenosineIBA 09/2010
1	4'-desmethoxyepisilvestrolIBA 02/2009

Therapy/Procedure

3	Therapeutics 01/2019 - 06/2013